Neutralizing antibody responses against SARS-CoV-2 in vaccinated people with multiple sclerosis.

Tirisham Victoria GyangJohn P EvansJoseph S MillerKariss AlcornJuan PengErica H BellCong ZengRichard GuminaShan-Lu LiuBenjamin M Segal

Published in: Multiple sclerosis journal - experimental, translational and clinical (2022)

We demonstrate that pwMS exhibit reduced nAb response to mRNA vaccination dependent on DMT status and identify predictive biomarkers for vaccine efficacy. We conclude that additional vaccination strategies may be necessary to achieve protective immunity in pwMS.

Keyphrases

sars cov
multiple sclerosis
respiratory syndrome coronavirus
white matter
dengue virus
binding protein
zika virus