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Associations between vaginal bacteria implicated in HIV acquisition risk and proinflammatory cytokines and chemokines.

Michelle C SaboDara A LehmanBingjie WangBarbra A RichardsonSujatha SrinivasanLusi OsbornDaniel MatemoJohn KinuthiaTina L FiedlerMatthew M MunchAlison L DrakeDavid N FredricksJulie OverbaughGrace John-StewartR Scott McClellandSusan M Graham
Published in: Sexually transmitted infections (2019)
This study provides evidence that several highly correlated vaginal bacterial taxa may influence vaginal cytokine and chemokine concentrations. These results suggest a mechanism where the presence of specific bacterial taxa could influence HIV susceptibility by increasing vaginal inflammation.
Keyphrases
  • antiretroviral therapy
  • hiv positive
  • hiv infected
  • human immunodeficiency virus
  • hiv testing
  • hepatitis c virus
  • hiv aids
  • men who have sex with men
  • oxidative stress
  • south africa