Associations between vaginal bacteria implicated in HIV acquisition risk and proinflammatory cytokines and chemokines.
Michelle C SaboDara A LehmanBingjie WangBarbra A RichardsonSujatha SrinivasanLusi OsbornDaniel MatemoJohn KinuthiaTina L FiedlerMatthew M MunchAlison L DrakeDavid N FredricksJulie OverbaughGrace John-StewartR Scott McClellandSusan M GrahamPublished in: Sexually transmitted infections (2019)
This study provides evidence that several highly correlated vaginal bacterial taxa may influence vaginal cytokine and chemokine concentrations. These results suggest a mechanism where the presence of specific bacterial taxa could influence HIV susceptibility by increasing vaginal inflammation.