A study of the phenotypic variability and disease progression in Laing myopathy through the evaluation of muscle imaging.
Nuria MuelasMarina FrasquetFernando Más-EstellésPilar MartíLaura Martínez-VicenteTeresa SevillaInmaculada AzorínJavier Poyatos-GarcíaHerminia Argente-EscrigRoger VílchezJuan Francisco Vázquez CostaLuis BatallerJuan J VilchezPublished in: European journal of neurology (2020)
We confirmed that the anterior leg compartment is systematically affected in Laing myopathy and may represent the only manifestation of this disorder. However, widespread muscle involvement in preferential but variable and not distance-dependent patterns was frequently observed. Imaging score analysis is useful to categorize patients and to follow disease progression over time.