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Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy.

Yuxin ZhaoHaiyong WangChengwei He
Published in: Journal of cancer research and clinical oncology (2021)
In this review, we discuss the mechanisms of EGFR-TKIs drug resistance and the clinical strategies to overcome drug resistance from the perspective of EGFR-TKIs combined treatment.
Keyphrases
  • epidermal growth factor receptor
  • advanced non small cell lung cancer
  • small cell lung cancer
  • tyrosine kinase