ClC-c regulates the proliferation of intestinal stem cells via the EGFR signalling pathway in Drosophila.

Jinping HuangXiao ShengZhangpeng ZhuoDanqing XiaoKun WuGang WanHaiyang Chen

Published in: Cell proliferation (2021)

Our findings reveal an ISC-specific function of ClC-c in regulating stem cell maintenance and proliferation, thereby providing new insights into the functional links among the chloride channel family, ISC proliferation and tissue homeostasis.

Keyphrases

stem cells
signaling pathway
small cell lung cancer
tyrosine kinase
cell therapy
mesenchymal stem cells
dna methylation