Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis.

Almusaedi AseelPeter McCarthyAlsaddi Mohammed

Published in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2023)

MR spectroscopy is effective in distinguishing recurrent brain tumors from necrosis. Our meta-analysis revealed that Cho/NAA, Cho/Cr, and NAA/Cr ratios were significantly better predictor of detected recurrent tumor. Therefore, the MRSI is an informative tool in the distinction of tumor recurrence versus necrosis.

Keyphrases

systematic review
high resolution
white matter
low grade
resting state
single molecule
computed tomography
radiation therapy
radiation induced
brain injury