RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis.

Jing TianEnqi KongXiangyu WangZhaoguang XieCherry Yin-Yi ChangJim Jinn-Chyuan SheuQuan HaoLi Sun

Published in: OncoTargets and therapy (2020)

These data demonstrate that RSF-1 siRNA enhanced the sensitivity of radiotherapy, and targeting RSF-1 may be a promising approach for the development of novel radiosensitizing agents for the treatment of cervical cancer.

Keyphrases

cell cycle
dna damage
cancer therapy
oxidative stress
cell proliferation
early stage
radiation therapy
cell death
endoplasmic reticulum stress
dna repair
electronic health record
locally advanced
hyaluronic acid
big data
machine learning
squamous cell carcinoma
signaling pathway
rectal cancer