Off-treatment bone mineral density changes in postmenopausal women receiving anastrozole for 5 years: 7-year results from the IBIS-II prevention trial.

Ivana SestakGlen BlakeRaj PatelJack CuzickAnthony HowellRobert ColemanRichard Eastell

Published in: British journal of cancer (2021)

These are the first results reporting BMD changes after stopping anastrozole in a breast cancer prevention setting. Our results show that the negative effects of anastrozole on BMD in the preventive setting are partially reversible.

Keyphrases

postmenopausal women
bone mineral density
body composition
clinical trial
study protocol
phase ii
adverse drug
smoking cessation