Rapid recovery of male cats with postrenal acute kidney injury by treating with allogeneic adipose mesenchymal stem cell-derived extracellular vesicles.

Weihui LiWei WangXin HeZheng LiaoAili AierkenJinlian HuaYan WangDezhang LuShiqiang Zhang

Published in: Stem cell research & therapy (2022)

We demonstrate the efficacy of ADMSCEVs in the treatment of PR-AKI on cats. Our study also suggests six metabolites to be novel PR-AKI markers and to be potential targets for ADMSCEVs therapy. Our findings will be useful to improve clinical treatment of both animal and human PR-AKI patients with ADMSCEVs in the future.

Keyphrases

acute kidney injury
bone marrow
endothelial cells
stem cell transplantation
adipose tissue
type diabetes
combination therapy
metabolic syndrome
risk assessment
climate change
human health
induced pluripotent stem cells
quantum dots