MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas.
Elies Fuster-GarciaDavid Lorente EstellésMaría Del Mar Álvarez-TorresJavier Juan-AlbarracínEduard ChelebianAlex RoviraCristina Auger AcostaJose PinedaLaura OleagaEnrique Mollá-OlmosSilvano FilicePaulina Due-TønnessenTorstein R MelingKyrre E EmblemJuan M García-GómezPublished in: European radiology (2020)
• MRI perfusion provides complementary prognostic information to MGMT methylation. • MGMT methylation improves prognosis in glioblastoma patients with moderate vascular profile. • Failure to consider these relations may lead to bias in the interpretation of clinical studies.