BMI change during childhood, DNA methylation change at TXNIP, and glucose change during midlife.

Hao MaXuan WangZhaoxia LiangXiang LiYoriko HeianzaJiang HeWei ChenLydia A Bazzano Lu Qi

Published in: Obesity (Silver Spring, Md.) (2023)

These results indicate that changes in blood DNAm at TXNIP are significantly associated with changes in FPG in midlife, and this association was modified by BMI trends during childhood and adolescence.

Keyphrases

dna methylation
body mass index
nlrp inflammasome
depressive symptoms
gene expression
weight gain
early life
genome wide
type diabetes
childhood cancer
metabolic syndrome
physical activity
weight loss
nk cells