Effectiveness and safety of mono- and add-on perampanel in pediatric patients with epilepsy: experience from a single-center retrospective study.

Yue Li Hong-Li GuoHu Ya-HuiJie WangZhang Yuan-YuanJian HuangJing XuChen JingLu Xiao-PengChen Feng

Published in: Epilepsia open (2023)

This study provides effectiveness and safety data on Chinese children with epilepsy treated with PER either as MT or as AT. The efficacy of patients receiving MT was much better than cases administered with more than 2 ASMs or diagnosed with drug-resistant epilepsy. In addition, no association was found between the plasma PER concentration and efficacy or safety.

Keyphrases

drug resistant
multidrug resistant
acinetobacter baumannii
electronic health record
temporal lobe epilepsy
big data
pseudomonas aeruginosa
deep learning
newly diagnosed