Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Berberine in the Treatment of Ischaemic Stroke.

Ke SongYikun SunHaoqi LiuYuanyuan LiNa AnLiqin WangHanlai ZhangFan Yang Yanwei Xing Yonghong Gao

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

The potential targets and biological effects of berberine in the treatment of ischaemic stroke were predicted in this study. The lncRNA H19/EGFR/JNK1/c-Jun signalling pathway may be a key mechanism of berberine-induced neuroprotection in ischaemic stroke.

Keyphrases

small cell lung cancer
cell death
tyrosine kinase
risk assessment
high glucose
climate change
endothelial cells
drug induced