IRONMAN: A Novel International Registry of Men With Advanced Prostate Cancer.
Lorelei A MucciJacob VinsonTheresa GoldTravis A GerkeJulie FilipenkoRebecca M GreenSimon George AndersonSimone Ann Marie BadalAnders BjartellKim N ChiIan D DavisDeborah EntingAndré P FayJohn LazarusJoaquin MateoRay S McDermottFolakemi T OdedinaDavid OlmosAurelius G OmlinAdemola Alabi PopoolaCamille C RaginRobin RobertsKjell M RussnesCharles WaihenyaKonrad H StopsackTerry HyslopPaul VillantiPhilip W KantoffDaniel J Georgenull nullPublished in: JCO global oncology (2022)
To our knowledge, this is the first international cohort of people newly diagnosed with advanced prostate cancer designed to describe variations in patient management, experiences, and outcomes. IRONMAN aims to identify optimal treatment sequences to improve survival, understand patient-reported outcomes, and explore novel biomarkers to understand treatment resistance mechanisms. Insights from IRONMAN will inform and guide future clinical management of people with mHSPC and CRPC. This cohort study will provide real-world evidence to facilitate a better understanding of the survivorship of people with advanced prostate cancer.