Prospective Observational Study of Volatile Sedation with Sevoflurane After Aneurysmal Subarachnoid Hemorrhage Using the Sedaconda Anesthetic Conserving Device.
Jan LeppertJan KüchlerAndreas WagnerNiclas HinselmannClaudia DitzPublished in: Neurocritical care (2024)
Sevoflurane appears to be a feasible alternative to intravenous sedation in patients with aSAH without intracranial hypertension, as our study did not show negative effects on ICP, cerebral oxygenation, or brain metabolism. Nevertheless, the risk of a decrease of MAP leading to a consecutive CPP decrease should be considered.
Keyphrases
- blood pressure
- mechanical ventilation
- high dose
- subarachnoid hemorrhage
- cerebral ischemia
- white matter
- resting state
- neoadjuvant chemotherapy
- squamous cell carcinoma
- intensive care unit
- low dose
- functional connectivity
- radiation therapy
- mass spectrometry
- gas chromatography
- extracorporeal membrane oxygenation
- arterial hypertension