S-conLSH: alignment-free gapped mapping of noisy long reads.

S-conLSH is one of the first alignment-free reference genome mapping tools achieving a high level of sensitivity. The spaced-context is especially suitable for extracting distant similarities. The variable-length spaced-seeds or patterns add flexibility to the proposed algorithm by introducing gapped mapping of the noisy long reads. Therefore, S-conLSH may be considered as a prominent direction towards alignment-free sequence analysis.