Iron-sulphur cluster biogenesis factor LYRM4 is a novel prognostic biomarker associated with immune infiltrates in hepatocellular carcinoma.

Yilin PangGuoqiang TanXunjun YangYuanshan LinYao ChenJinping ZhangTing XieHuaibin ZhouJun FangQiongya ZhaoXiaojun RenJianghui LiJianxin LyuZheng Wang

Published in: Cancer cell international (2021)

LYRM4 could be a novel prognostic biomarker and molecular target for LIHC therapy. In particular, the potential regulatory networks of LYRM4 overexpression in LIHC provide a scientific basis for future research on the role of the ISC assembly mechanism and LYRM4-mediated sulphur transfer routes in carcinogenesis.

Keyphrases

transcription factor
cell proliferation
human health
risk assessment
iron deficiency
smoking cessation
replacement therapy