Plasma exchange as a tool for removal of bevacizumab: Highlighting application for urgent surgery.
Byran J NethJeffrey L WintersRevathi Thirumushi SairajAli Gharibi LoronMasum RahmanRenee HirteCecile Riviere-CazauxMichael W RuffTerry C BurnsPublished in: Neuro-oncology practice (2023)
We report a complex clinical scenario of a patient requiring urgent wound washout 4 days after last bevacizumab infusion for CNS infection. Surgery was successfully performed without new complications with use of TPE to remove bevacizumab immediately following surgery. This case highlights the feasibility of this approach, which may be utilized effectively in patients requiring surgery after having recently received bevacizumab.