The Genetic and Epigenetic Mechanisms Involved in Irreversible Pulp Neural Inflammation.

Xiaoxi Xi Yihong Ma Yuzhen Xu Anthony Chukwunonso Ogbuehi Xiangqiong Liu Yupei Deng Junming Xi Haitong Pan Qian Lin Bo Li Wanchen Ning Xiao Jiang Hanluo Li Simin Li Xianda Hu

Published in: Disease markers (2021)

This paper demonstrates the genetic and epigenetic mechanisms of irreversible pulpitis by revealing the ceRNA network. The biomarkers identified could provide research direction for the application of genetically modified stem cells in endodontic regeneration.

Keyphrases

stem cells
dna methylation
genome wide
gene expression
oxidative stress
copy number
long non coding rna
network analysis