Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques.
Hayden N BrochuElise SmithSangmi JeongMichelle CarlsonScott G HansenJennifer Tisoncik-GoG Lynn LawLouis J PickerMichael GaleXinxia PengPublished in: bioRxiv : the preprint server for biology (2024)
Our findings indicate that changes in gut microbiomes are associated with RhCMV/SIV vaccine-induced protection and early host response to vaccination in rhesus macaques.