Pentosidine concentration is associated with degenerative lumbar scoliosis in older women: preliminary results.
Yawara EguchiToru ToyoguchiKazuhide InageKazuki FujimotoSumihisa OritaKazuyo YamauchiMiyako SuzukiHirohito KanamotoKoki AbeMasaki NorimotoTomotaka UmimuraMasao KodaTakeo FuruyaYasuchika AokiKazuhisa TakahashiSeiji OhtoriPublished in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2017)
We found that sarcopenia was involved in DLS, and high serum pentosidine levels are associated with severity of coronal and sagittal malalignment in older women, suggesting that high levels of AGEs are a potential biomarker for the progression of lumbar scoliosis and kyphotic deformity. Further studies are needed to clarify the pathogenesis of DLS.