Leukemia Inhibitory Factor-Loaded Nanoparticles with Enhanced Cytokine Metabolic Stability and Anti-Inflammatory Activity.

Stephanie M DavisDerek ReichelYounsoo BaeKeith R Pennypacker

Published in: Pharmaceutical research (2018)

NanoLIF and CD11b-NanoLIF preserved the metabolic stability and biological activity of LIF in vitro. These results are promising to improve the therapeutic potential of LIF in treating neurodegenerative and inflammatory diseases.

Keyphrases

drug delivery
acute myeloid leukemia
bone marrow
oxidative stress
cancer therapy
wound healing
walled carbon nanotubes