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The recombination landscape of the Khoe-San likely represents the upper limits of recombination divergence in humans.

Gerald van EedenCaitlin UrenEvlyn PlessMira MastorasGian D van der SpuyGerard C TrompBrenna M HennMarlo Möller
Published in: Genome biology (2022)
Fine-scale differences in recombination can meaningfully alter the results of a selection scan. The recombination map we infer likely represents an upper bound on the extent of divergence we expect to see for a recombination map in humans and would be of interest to any researcher that wants to test the sensitivity of population genetic or GWAS analysis to recombination map input.
Keyphrases
  • dna repair
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  • computed tomography
  • high density
  • oxidative stress
  • gene expression
  • single cell
  • genome wide association study
  • dual energy