Loss of CEACAM1 in hepatocytes causes hepatic fibrosis.

Sobia ZaidiSuman AsallaHarrison T MuturiLucia RussoRaziyeh AbdolahipourGetachew Debas BelewMaria Benitez IglesiasMary FeraudoLensay LeonEnoch KuoXiuli LiuSivarajan KumarasamyHilda E GhadiehCara Gatto-WeisAli ZarrinparSergio DuarteSonia M Najjar

Published in: European journal of clinical investigation (2024)

mice assigned a key role to CEACAM1 loss from hepatocytes in hepatic fibrosis independently of other liver cells.

Keyphrases

induced apoptosis
liver injury
cell cycle arrest
high fat diet induced
liver fibrosis
endoplasmic reticulum stress
oxidative stress
signaling pathway
cell proliferation
insulin resistance