Utility of a Cell-Direct Polymerase Chain Reaction-Based Nucleic Acid Lateral Flow Immunoassay for Detection of Bacteria in Peripheral Blood Leukocytes of Suspected Sepsis Cases.
Haruka ImaiYuji WatanabeDaishi ShimadaJun SuzukiShiro EndoMitsuo KakuMasafumi SekiPublished in: Infection and drug resistance (2021)
Blood culture tests are probably the gold standard in identifying causative organisms in sepsis, but the rapid results from cdPCR-NALFIA simultaneously used with blood culture may make it an important auxiliary diagnostic tool for identifying infecting organisms and lead to the improvement of mortality of the septic patients, because these combined results provide the wide information on the possible pathogens in early phase.
Keyphrases
- peripheral blood
- nucleic acid
- acute kidney injury
- gram negative
- end stage renal disease
- loop mediated isothermal amplification
- intensive care unit
- newly diagnosed
- ejection fraction
- chronic kidney disease
- septic shock
- prognostic factors
- single cell
- pulmonary embolism
- multidrug resistant
- stem cells
- sensitive detection
- peritoneal dialysis
- bone marrow
- real time pcr
- mesenchymal stem cells