Role of tryptophan-metabolizing microbiota in mice diarrhea caused by Folium sennae extracts.

Chenyang ZhangHaoqing ShaoDandan LiNenqun XiaoZhou-Jin Tan

Published in: BMC microbiology (2020)

Folium sennae targeted cytochrome P450 3A4 to alter intestinal bacterial characteristic and intervene the tryptophan metabolism of intestinal microbiota, such as Streptococcus, Sutterella and Dorea, which could be the intestinal microecological mechanism of diarrhea caused by Folium sennae extracts.

Keyphrases

irritable bowel syndrome
clostridium difficile
candida albicans
cancer therapy
biofilm formation
high fat diet induced
pseudomonas aeruginosa
insulin resistance