Sex differences in the medial prefrontal cortical glutamate system.

Melissa C KnouseAnna G McGrathAndre U DeutschmannMatthew T RichLia J ZallarAnjali M RajadhyakshaLisa A Briand

Published in: Biology of sex differences (2022)

Overall, we conclude that there are sex differences in glutamatergic transmission in the mPFC. Our data suggest that females have higher levels of glutamatergic transmission in this region. This provides evidence that the development of sex-specific pharmacotherapies for various psychiatric diseases is important to create more effective treatments.

Keyphrases

mental health
working memory
functional connectivity
big data
transcranial magnetic stimulation
machine learning
artificial intelligence