Characterization, localization and comparison of c-Kit+ lung cells in never smokers and smokers with and without COPD.

Alejandra López-GiraldoTamara CruzLaureano MolinsÁngela GuiraoAdela SacoSandra CuerpoJosep RamirezÁlvar AgustíRosa Faner

Published in: BMC pulmonary medicine (2018)

The adult human lung contains a mixture of c-Kit+ cells, unlikely to be lung stem cells, which are independent of smoking status and/or presence of COPD.

Keyphrases

induced apoptosis
stem cells
smoking cessation
cell cycle arrest
chronic obstructive pulmonary disease
lung function
cell death
signaling pathway
oxidative stress
mesenchymal stem cells
air pollution
bone marrow
cell therapy
pi k akt