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Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer: French NutriNet-Santé study.

Salam BashirLeopold K FezeuShani Leviatan Ben-AryeSharon YehudaEliran Moshe ReuvenFabien Szabo de EdelenyiImen Fellah-HebiaThierry Le TourneauBerthe Marie Imbert-MarcilleEmmanuel B DrouetMathilde TouvierJean-Christian RousselHai YuXi ChenSerge HercbergEmanuele CozziJean-Paul SoulillouPilar GalanVered Padler-Karavani
Published in: BMC medicine (2020)
We found a clear link between the levels and repertoire of serum anti-Neu5Gc IgG and Neu5Gc intake from red meat and dairy. These precise rational methodologies allowed to develop a Gcemic index to simplify the assessment of Neu5Gc in foods that could potentially be adapted for dietary recommendations to reduce cancer risk.
Keyphrases
  • gas chromatography
  • papillary thyroid
  • mass spectrometry
  • body mass index
  • weight gain
  • young adults
  • tandem mass spectrometry
  • weight loss