Metabolic impairments associated with type 2 diabetes mellitus and the potential effects of exercise therapy: An exploratory randomized trial based on untargeted metabolomics.
Furong ZhangXixi ChenMingxiao YangXiaoyu ShenYiliang WangDongling ZhongFang ZengRongjiang JinPublished in: PloS one (2024)
T2DM patients displayed impaired carbohydrate, lipid, and amino acid metabolism, and exercise therapy improved their metabolic health. Different modalities may act through different pathways. Tai Chi may improve disrupted BCAAs metabolism, whereas brisk walking mainly regulates steroid hormone biosynthesis and arachidonic acid metabolism.
Keyphrases
- end stage renal disease
- mass spectrometry
- high intensity
- amino acid
- ejection fraction
- physical activity
- chronic kidney disease
- healthcare
- newly diagnosed
- public health
- mental health
- resistance training
- prognostic factors
- stem cells
- adipose tissue
- patient reported outcomes
- high resolution
- mesenchymal stem cells
- risk assessment
- climate change
- liquid chromatography
- body composition
- social media
- gas chromatography mass spectrometry
- health promotion