Therapeutic potential of boswellic acids: an update patent review (2016-2023).
Hidayat HussianDaijie WangHesham R El-SeediLuay RashanIshtiaq AhmedMuzaffar AbbasNilufar Z MamadalievaHaider N SultaniMuhammad Iftikhar HussainSyed Tasadaque A ShahPublished in: Expert opinion on therapeutic patents (2024)
H functional groups. In particular, the C-24 amide and amino analogues have shown enhanced anticancer effects compared to the parent AKBA. In addition, BAs have the ability to form conjugates with other antiviral, anti-inflammatory and anticancer drugs that synergistically enhance their biological efficacy. In addition, this conjugation strategy will increase the solubility and bioavailability of BAs, which is one of the most important issues in the development of BAs.