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A case of intestinal amoebiasis mimicking intestinal Behçet's disease.

Ayaka FukuiYoichi NakayamaTsuneyasu YoshidaKosaku MurakamiKeiichiro KadobaHideo OnizawaShuji AkizukiRan NakashimaHajime YoshifujiKoichiro OhmuraAkihiko SugimotoShuji YamamotoAkio Morinobu
Published in: Modern rheumatology case reports (2022)
Intestinal amoebiasis is caused by Entamoeba histolytica (E. histolytica) and is characterised by cecal lesions, multiple lesions, aphthae, and multiple exudative erosions. Intestinal Behçet's disease (BD) is a chronic inflammatory disorder that is characterised by multiple ulcers. Although the aetiologies of these two bowel diseases are unrelated, they are difficult to distinguish because they present similarly with inflammation and ulcers, especially if evidence of specific pathogens is not detected. Herein, we report a case of intestinal amoebiasis in a patient with BD. The patient underwent colonoscopy four times before intestinal amoebiasis was diagnosed. As intestinal BD was initially suspected, she received high-dose glucocorticoid therapy, which exacerbated her condition. Following exacerbation, she underwent colonoscopy, and E. histolytica was revealed. Deliberate care should be taken to distinguish between intestinal amoebiasis and intestinal BD, as the appropriate treatments for these diseases are entirely different.
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