Associations of Sleep Duration and Daytime Sleepiness with Plasma Amyloid Beta and Cognitive Performance in Cognitively Unimpaired, Middle-Aged and Older Adult African Americans.
Jesse D CookAmmara MalikDavid T PlanteDerek NortonRebecca Langhough KoscikLianlian DuBarabara B BendlinKris M KirmessMary S HolubaschMatthew R MeyerVenky VenkateshTim WestPhilip B VergheseKevin E YarasheskiKevin V ThomasCynthia M CarlssonSanjay AsthanaSterling C JohnsonCarey E GleasonMegan ZuelsdorffPublished in: Sleep (2023)
SRSD was below National Sleep Foundation recommendations and daytime sleepiness was prevalent in this cohort. In the absence of observed associations with plasma Aβ, poorer self-reported sleep health broadly predicted poorer cognitive function but not accelerated decline. Future research is necessary to understand and address modifiable sleep mechanisms as they relate to cognitive aging in AA at disproportionate risk for dementia.