The SP1-12LOX axis promotes chemoresistance and metastasis of ovarian cancer.

Qi ZhangGuifang YanJuan LeiYu ChenTing WangJuan GongYong ZhouHuakan ZhaoHao ChenYu ZhouLei WuJiangang ZhangXiao ZhangJingchun WangYongsheng Li

Published in: Molecular medicine (Cambridge, Mass.) (2020)

Our results reveal that SP1-12LOX axis signaling plays a key role in DDP-resistance and metastasis, which provide a new therapeutic target for ovarian cancer.

Keyphrases

genome wide
single cell