Genotypic, proteomic, and phenotypic approaches to decipher the response to caspofungin and calcineurin inhibitors in clinical isolates of echinocandin-resistant Candida glabrata.
Andres Ceballos-GarzonLucia MonteolivaConcha GilCarlos Alvarez-MorenoNelson E Vega-VelaDavid M EngelthalerJolene BowersPatrice Le PapeClaudia Marcela Parra-GiradoPublished in: The Journal of antimicrobial chemotherapy (2021)
Our findings confirm that calmodulin-calcineurin-Crz1 could provide a relevant target in life-threatening invasive candidiasis.