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Incidence, characteristics, and management of central nervous system metastases in patients with inflammatory breast cancer.

Laura E G WarrenSamuel M NimanMarie C RemolanoJean M LandryFaina NakhlisJennifer R BellonAyal A AizerNancy U LinSara M TolaneyMeredith M ReganBeth A OvermoyerFilipa C Lynce
Published in: Cancer (2022)
Patients with IBC, particularly those with triple-negative IBC, visceral metastasis, and those at a younger age at diagnosis of metastatic disease, are at significant risk of developing mCNS. Further investigation into prevention of mCNS and whether early detection of mCNS is associated with improved IBC patient outcomes is warranted.
Keyphrases
  • squamous cell carcinoma
  • small cell lung cancer
  • risk factors
  • oxidative stress
  • insulin resistance
  • cerebrospinal fluid
  • type diabetes
  • adipose tissue
  • skeletal muscle