Thymidine kinase 1 silencing retards proliferative activity of pancreatic cancer cell via E2F1-TK1-P21 axis.
Xiaole ZhuChenyuan ShiYunpeng PengLingdi YinMin TuQiuyang ChenChaoqun HouQiang LiYi MiaoPublished in: Cell proliferation (2017)
The results suggested that TK1 might be involved in the development and progression of PDAC by regulating cell proliferation and show that TK1 may work as a promising therapeutic target in patients with PDAC.