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Genotyping of cerebrospinal fluid in lung cancer patients with leptomeningeal metastasis.
Naifu Nie
Haodong Zhou
Kejun Zhang
Lan Liu
Nuo Luo
Renyuan Wang
Xin Li
Mengxiao Zhu
Chen Hu
Yubo Wang
Zhulin Liu
Li Li
Yong He
Published in:
Thoracic cancer (2022)
In conclusion, CSF could be superior to plasma in providing a more comprehensive genetic landscape of LM to find out drug resistance mechanisms and guide subsequent treatments.
Keyphrases
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cerebrospinal fluid
genome wide
dna methylation
high throughput
copy number
single cell
genetic diversity
small cell lung cancer
gene expression
brain metastases