Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood.

Sigurgeir Olafsson Kristjan F AlexanderssonJohann G K GizurarsonKatrin HauksdottirOrvar GunnarssonJulius GudmundssonSimon N StaceyGardar SveinbjornssonJona SaemundsdottirEinar S BjornssonSigurdur BjornssonKjartan B OrvarArnor VikingssonArni J GeirssonSturla ArinbjarnarsonGyda Bjornsdottir Thorgeir E Thorgeirsson Snaevar SigurdssonGisli H HalldorssonOlafur T MagnussonGisli MassonHilma HolmIngileif JonsdottirOlof SigurdardottirGudmundur I EyjolfssonPatrick SulemUnnur ThorsteinsdottirThorvaldur JonssonThorunn RafnarDaniel F GudbjartssonKari Stefansson

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)

Genetic correction of biomarker values could improve prediction algorithms and decision-making based on these biomarkers.

Keyphrases

decision making
copy number
machine learning
genome wide
deep learning