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Gut microbiota profile and selected plasma metabolites in type 1 diabetes without and with stratification by albuminuria.

Signe Abitz WintherPeter HenriksenJosef K VogtTue Haldor HansenLinda AhonenTommi SuvitaivalEmilie Hein ZobelMarie Frimodt-MøllerTine Willum HansenTorben HansenHans-Henrik ParvingCristina Legido-QuigleyEllen BurgessOluf Pedersen
Published in: Diabetologia (2020)
We demonstrate that individuals with type 1 diabetes of long duration are characterised by aberrant profiles of gut microbiota and plasma metabolites. Moreover, individuals with type 1 diabetes with initial stages of diabetic nephropathy show different gut microbiota and plasma metabolite profiles depending on the level of albuminuria. Graphical abstract.
Keyphrases
  • diabetic nephropathy
  • type diabetes
  • ms ms
  • cardiovascular disease
  • glycemic control
  • adipose tissue
  • weight loss