Effect of Corticosteroid on Immunogenicity of SARS-CoV-2 Vaccines in Patients With Solid Cancer.
Chayanee SamdaengpanPrakongboon SungkasubunWorawit ChaiwiriyawongArchara SupavavejJomtana SiripaibunChumut PhanthunaneWalaipan TantiyavarongWisut LamlertthonTeerapat UngtrakulKriangkrai TawinpraiKamonwan SoonklangThitapha ThongchaiPiyarat LimpawittayakulPublished in: JCO global oncology (2024)
Patients with solid cancer vaccinated against COVID-19 disease while receiving dexamethasone had lower immunogenicity responses than those who got vaccines without dexamethasone. The direct association between the immunogenicity level and steroid dosage, as well as length of duration from vaccination to dexamethasone, was observed.