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Immunohistochemical analysis of OTP and NKX6.1 in neuroendocrine tumors of the lung and pancreas.

Lorene M YoxtheimerJonas J HeymannCynthia CohenRema A RaoAbha GoyalMomin T Siddiqui
Published in: Diagnostic cytopathology (2018)
OTP may be useful in diagnosing well-differentiated NETs of pulmonary origin. NKX6.1 may have utility in segregating high from low-grade NETs of both pulmonary and pancreatic origin, although other methods will be required to determine site of origin.
Keyphrases
  • low grade
  • neuroendocrine tumors
  • pulmonary hypertension
  • high grade