Immunohistochemical analysis of OTP and NKX6.1 in neuroendocrine tumors of the lung and pancreas.
Lorene M YoxtheimerJonas J HeymannCynthia CohenRema A RaoAbha GoyalMomin T SiddiquiPublished in: Diagnostic cytopathology (2018)
OTP may be useful in diagnosing well-differentiated NETs of pulmonary origin. NKX6.1 may have utility in segregating high from low-grade NETs of both pulmonary and pancreatic origin, although other methods will be required to determine site of origin.