The muscle regeneration marker FOXP3 is associated with muscle injury in Duchenne muscular dystrophy.

Sthephanie Yannin Hernández-de la CruzThania Ordaz-RoblesMarco Antonio Villaldama-SorianoCristian Emmanuel Luna-GuzmánTomas Almeida-BecerrilJudith Villa-MoralesAlan Cárdenas-ConejoEugenia Dolores Ruíz-CruzJorge Maldonado-HernandezMariela Bernabe-GarciaLourdes Barbosa-CortésMaricela Rodríguez-Cruz

Published in: Brain & development (2024)

FOXP3 is highly expressed in circulating leukocytes of DMD patients with the worst muscle function. Omega-3 LCPUFAs might modulate the synthesis of the adhesion marker CD49d + CD8 + T-cells, but their plausible impact on FOXP3 needs more research.

Keyphrases

duchenne muscular dystrophy
regulatory t cells
skeletal muscle
stem cells
muscular dystrophy
dendritic cells
staphylococcus aureus
immune response