Patterns and predictors of first and subsequent recurrence in women with early breast cancer.
Y M GeurtsAnnemieke WitteveenR BretveldP M PoortmansG S SonkeL J A StrobbeS SieslingPublished in: Breast cancer research and treatment (2017)
Although the risk of subsequent recurrence is high, absolute incidence remains low. Also, almost half the second recurrences are detected in the first year after previous recurrence and more than 80% are DM. This suggests that more intensive follow-up for early detection subsequent recurrence is not likely to be (cost-)effective.