Atopic outcomes at 2 years in the CORAL cohort, born in COVID-19 lockdown.

Sadhbh HurleyRuth FranklinNaomi McCallionAideen M ByrneJohn FitzsimonsMartin WhiteCorina M Berset Jonathan O'Brien Hourihane

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2023)

Despite higher AD incidence in the CORAL cohort, the incidence of food sensitization and allergy are lower than expected pre-pandemic rates possibly reflecting the early introduction and maintenance of dietary allergens enhanced by changes in infant infections, antibiotic use, and breastfeeding in the first 2 years of life in the group. These beneficial effects of the lockdown could be outweighing the expected risk of less early-life microbial encounters outlined by the hygiene hypothesis.

Keyphrases

early life
coronavirus disease
sars cov
risk factors
preterm infants
atopic dermatitis
microbial community
low birth weight
type diabetes
gestational age
metabolic syndrome
skeletal muscle
preterm birth