Interval-dependent neurotoxicity after multiple ketamine injections in late postnatal mice.

Yulim LeeAnn Misun YounXianshu JuJianchen CuiBoohwi HongSangwon YunYoungkwon KoYoon Hee KimJun Young HeoWoosuk Chung

Published in: Journal of anesthesia (2020)

Multiple ketamine injections induce interval-dependent, long-lasting synaptic changes and behavioral impairments. Future studies should carefully consider the dosing interval as a significant factor when studying the neurotoxic effects of multiple anesthetic exposures.

Keyphrases

pain management
platelet rich plasma
preterm infants
adipose tissue
current status