Defining the Genetic Landscape of Congenital Mirror Movements in 80 Affected Individuals.

Meagan L Collins HutchinsonJudith St-OngeSabrina SchliengerNassima Boudrahem-AddourLina MougharbelJean-Francois MichaudClara LloydElena BruneauCedric RouxAhmed N SahlyBradley OstermanKenneth A MyersGuy A RouleauDaniel Alexander Jimenez CruzJean-Baptiste RivièreAndrea AccogliFrederic CharronMyriam Srour

Published in: Movement disorders : official journal of the Movement Disorder Society (2024)

A genetic etiology can be identified in one third of CMM individuals, with DCC being the most common gene involved. Two thirds of CMM individuals were unsolved, highlighting that CMM is genetically heterogeneous and other CMM genes are yet to be discovered. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

genome wide
copy number
dna methylation
gene expression
systematic review
transcription factor
genome wide analysis