Transcriptome Profiling of ADAR1 Targets in Triple-Negative Breast Cancer Cells Reveals Mechanisms for Regulating Growth and Invasion.

Allison R BakerChristos MiliotisJulia Ramírez-MoyaTalia MarcIoannis S VlachosPilar Santisteban Frank J Slack

Published in: Molecular cancer research : MCR (2022)

Targeting ADAR1 and thus downstream FLNB editing and miRNA regulation represents a possible novel therapeutic strategy in triple-negative breast cancer.

Keyphrases

breast cancer cells
single cell
crispr cas
rna seq
cell migration
gene expression
cancer therapy
genome wide
drug delivery
dna methylation