The combination of doxazosin and metyrosine as a preoperative treatment for pheochromocytomas and paragangliomas.
Yuka OhmachiMasaaki YamamotoYuiko InabaShohei MakinoShin UraiRisa MatsumotoHironori BandoKeitaro KanieYasutaka TsujimotoYuma MotomuraYuriko SasakiYuka Oi-YoNaoki YamamotoMasaki SuzukiMichiko TakahashiGenzo IguchiMaki KanzawaJunya FurukawaKatsumi ShigemuraSatoshi MizobuchiWataru OgawaHidenori FukuokaPublished in: Endocrine (2024)
The combination of metyrosine and doxazosin as a preoperative treatment for PPGLs affects intraoperative circulatory hemodynamics, such as a reduced occurrence of blood pressure elevation during surgery. Further research is necessary to identify patients who will benefit most from this combination treatment.