Young investigator challenge: Can the Ion AmpliSeq Cancer Hotspot Panel v2 be used for next-generation sequencing of thyroid FNA samples?

Claudio BellevicineRoberta SgarigliaUmberto MalapelleElena VigliarMariantonia NacchioGiuseppe CianciaMarkus EszlingerRalf PaschkeGiancarlo Troncone

Published in: Cancer cytopathology (2016)

CHPv2 is a valid option for the molecular evaluation of thyroid FNA specimens by NGS. It is interesting to note that this approach is accurate and effective even when applied to routine cytology samples that usually do not have optimal preanalytical and postsequencing requirements. Cancer Cytopathol 2016;124:776-84. © 2016 American Cancer Society.

Keyphrases

papillary thyroid
squamous cell
fine needle aspiration
lymph node metastasis
squamous cell carcinoma
high resolution
gene expression
childhood cancer
clinical practice
ultrasound guided
high grade
copy number
middle aged